5 Essential Elements For cees dekker
5 Essential Elements For cees dekker
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Rotary movement of DNA rotors on nanopores. Leading row: Uncooked video clip of your Cy5 channel of every rotor. Center row: corresponding solitary-particle localization results of both equally ends with the DNA rotors. The place of the present frame is marked as orange and blue dots, as well as trajectory of the 10 frames right before the current frame is shown as reliable lines.
You often become involved in discussions about science and religion. You've also penned many books on the subject. Don’t you think that eventually we will know anything and that God’s job will likely be over?
[Laughs] ‘It had been undoubtedly a fantastic threat! At time, I was well aware that it could go wrong Which I could develop into a lot less productive, but I just dismissed that. Curiosity has usually been my strongest driving force. And fortunately all of it labored out.’
2007, first actual-time detection of strand Trade in homologous recombination by RecA; discovery of the minimal persistence duration of ends of microtubules; and settled the system of biosensing with carbon nanotubes
Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent design in 2005. (nl)
SMC complexes can pass physical roadblocks larger than their ring dimensions, indicating a nontopological system for DNA loop extrusion
All parameters had been precisely the same for every panel With this online video, except for the initial placement from the 6hb rod (proven in blue) about the nanopore. Simulations that terminated early resulting from translocation of your rod in the pore are marked by a gray background.
2011, 1st in vitro measurements of transport across just one biomimetic nuclear pore intricate; improvement of multiplexed magnetic tweezers for kilo-molecule experiments; and resolved the system of homology recognition in DNA homologous recombination
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1). The existing–voltage curves showed sizeable modulations with gate voltage, even at area temperature, which was consistent with band bending in a very ~0.6 eV bandgap semiconducting nanotube. These facts also showed the conductance might be modulated by 6 orders of magnitude by changing the gate voltage. The final results of the operate — a home-temperature transistor made out of only one carbon nanotube molecule — have been posted in Nature in May well 1998.
Considering that 2000 he moved to single-molecule biophysics and nanobiology, with exploration from reports of DNA loop extrusion and supercoiling to DNA translocation via nanopores. Much more a short while ago his investigation has focused on finding out chromatin construction and mobile division with germs on chip, though he can be attempting to eventually build artificial cells from The underside up.
Cees Dekker is Distinguished College Professor at TU Delft. Properly trained to be a physicist, he pioneered nanotechnology with lots of discoveries on carbon nanotubes in the nineteen nineties. Since 2000, https://www.ceesdekker.net he moved to one-molecule biophysics and nanobiology. His present-day investigate concentrates on (i) nanopores for protein sequencing; (ii) chromosome framework, specifically SMC motor protein; and (iii) creating a living synthetic mobile from lifeless molecules. Dekker can be an elected member of your KNAW and fellow to your APS as well as IOP.
Developments in nanotechnology in the 1990s produced creating electronic units from solitary molecules a likelihood. Cees Dekker recounts how his crew designed a area-temperature transistor based upon one carbon nanotube.
2004, discovery of latest physics in translocation of DNA via nanopores; initially experimental examine of ions conduction in nanofluidic channels; to start with electrochemistry with specific single-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; to start with electrical docking of microtubules on kinesin-coated nanostructures; 1st biophysics characterization of the mechanical Homes of double-stranded RNA; and first solitary-molecule analyze of DNA translocation by a restriction-modification enzyme.